Top ONE Network Editors’ Choice Reviews of 2022

Cataract/Anterior Segment, Comprehensive Ophthalmology, Cornea/External Disease, Oculoplastics/Orbit, Pediatric Ophth/Strabismus, Retina/Vitreous, Uveitis

The top 15 Editors’ Choice reviews in 2022, including the ocular effects of the COVID-19 virus and vaccinations for COVID-19, and a variety of updates from major journals across ophthalmology.

1. Rare ocular side effects have been noted after COVID-19 vaccination

By Danah Albreiki, MBBS
A narrative literature review of studies was conducted to provide an overview of the adverse ocular effects reported with the 4 types of COVID-19 vaccines currently available: mRNA, protein subunit, vector, and whole virus.

2. Onset of uveitis observed within 14 days of COVID-19 vaccination

By Ashleigh Laurin Levison, MD
Investigators used retrospective data to identify which uveitis-related diseases might be linked to COVID-19 vaccination.

3. New and worsening otologic symptoms are a side effect of teprotumumab

By Richard C. Allen, MD, PhD
Investigators at a single center in the United States reviewed real-world patient data on otologic issues related to teprotumumab treatment for thyroid eye disease.

4. Some nutritional supplements appear to have benefit in treating hair loss

By Anne Barmettler, MD
Nutritional supplements such as pumpkin seed oil capsules have been discussed as having potential for helping people with hair loss, with no serious adverse events.

5. Doxycycline shows efficacy in improving symptoms of thyroid-associated orbitopathy

By Richard C. Allen, MD, PhD
The short-term efficacy and safety of doxycycline vs placebo for mild thyroid-associated orbitopathy was assessed in a prospective, randomized, double-masked, parallel-group trial conducted in China.

6. Novel red-light therapy may help control childhood myopia

By Brenda L. Bohnsack, MD, PhD
This was the first prospective, randomized, multicenter study of repeated low-level red-light therapy for myopia control in children, a treatment currently approved in China for amblyopia.

7. Transconjunctival injection of botulinum toxin offers corneal protection

By Richard C. Allen, MD, PhD
A procedure involving modified transconjunctival injection of botulinum toxin was assessed for its safety and effectiveness in corneal protection.

8. Academy guidelines for Candida-related endophthalmitis screening now available

By Xuejing Chen, MD
The American Academy of Ophthalmology has published its recommendations against routine screening of patients for endophthalmitis caused by Candida septicemia.

9. Topical insulin appears to promote reepithelialization in neurotrophic keratitis

By Nandini Venkateswaran, MD
Topical insulin is assessed as an agent of reepithelialization in patients with stage 2 or 3 refractory neurotrophic keratitis.

10. Many factors can lead to intraoperative floppy iris syndrome during cataract surgery

By Leela V. Raju, MD
To provide insight into the factors that increase the risk of intraoperative floppy iris syndrome (IFIS), investigators conducted a systematic review and meta-analysis of recent IFIS studies.

11. Aspherical lenses slow myopia progression in children throughout 2-year study

By Brenda L. Bohnsack, MD, PhD
Investigators evaluated whether aspherical lenses slowed myopia progression throughout 2 years of use and whether the level of lens asphericity affected myopia control efficacy.

12. Patients with floppy eyelid syndrome have a high rate of obstructive sleep apnea

By Nikisha Q. Richards, MD, FACS
A systematic review and meta-analysis were conducted to investigate the prevalence of obstructive sleep apnea among patients with floppy eyelid syndrome.

13. The Belin ABCD grading system is useful for assessing keratoconus progression

By Christopher S. Sales, MD
Records from the Homburg Keratoconus Center (Germany) were used to evaluate the utility of the Belin ABCD grading system for diagnosing keratoconus and staging progression.

14. Biomarkers can help distinguish orbital cellulitis from ordinary inflammation

By Edward J. Wladis, MD
This study was a retrospective analysis of clinical findings and biomarkers used to distinguish between orbital cellulitis and idiopathic/nonspecific orbital inflammation.

15. Rates of postsurgical endophthalmitis have decreased and may go even lower

By Michael D. Patterson, DO
This study was conducted to determine the incidence of endophthalmitis in the United States and the risk factors in developing endophthalmitis after cataract surgery.

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