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Are patients with seborrheic dermatitis at risk for osteoporosis? — Donovan Hair Clinic


New Study Links Seborrheic Dermatitis With increased risk of Osteoporosis

Osteoporosis is a systemic bone-resorbing disease that causes bone fragility and subsequent risk of fracture. The WHO 1996 definition of osteoporosis includes four key components: 1) low bone mass, 2) microarchitectural detioration, 3) increase in fragility as a result of these and 4) increased susceptibility to fracture.

in addition, osteoporosis has been defined based on bone mineral density (BMD) assessment. According to the WHO criteria, osteoporosis is defined as a BMD that lies 2.5 standard deviations or more below the average value for young healthy women (i.e. a T-score of < − 2.5 SD).

Risk Factors for Osteoporosis

Risk factors for osteoporosis are divided into two categories: modifiable and non-modifiable. Modifiable risk factors include low body weight, smoking, alcohol consumption, lack of exercise, deficiency of dietary calcium, and long-term glucocorticoid use. The non-modifiable group includes gender, age, race, and genetic characteristics.

In a recent meta-analysis by Salari et al, the prevalence of osteoporosis in the world was 18.3%, which was calculated based on reports of the prevalence of osteoporosis from 86 studies across five continents.The sample size of the study was 103,334,579 people in the age range of 15–105 years. Subgroup analyses showed that for women the prevalence was 23.1 % and for men it was 11.7 %.

Seborrheic Dermatitis (SD)

Seborrheic dermatitis is an inflammatory skin condition that affects about 5 % of the world. It is thought to be multifactorial in nature with Malassezia yeast playing an important role in the condition. Changes in skin microbiome, as well as environmental factors play a key role too. All of the factors have yet to be fully worked out. The most common sites of SD, known as “seborrheic areas,” are the anterior chest, axilla, back, groin, central area of the face, and scalp. The incidence of SD is highest in infants, adolescents, and adults aged 30–60 years.

Risk Factors for Seborrheic Dermatitis

There are many well known risk factors for SD. Many of the seborrheic dermatitis risk factors are shown in the image below. They include

a) Row 1, top, left to right: neurological conditions like Parkinson’s and tardive dyskinesia, stress, being male, HIV, winter months.

b) Row 2, middle, left to tight: depression, sleep deprivation, humidity, Western diets, excess alcohol.

c) Row 3, bottom, left to right: darker skin types, altitude, some medications, lymphoma and immunosuppressive states).



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