Chris Cederroth | British Tinnitus Association
I am currently an Associate Professor at the Karolinska Institutet in Sweden.
I am a biologist with 11 years of professional research experience in academia. My PhD, awarded in Geneva (Switzerland), aimed at understanding the effects and characterizing the molecular mechanisms of endocrine disruption mediated by phytoestrogens on sexual development, reproduction and metabolism.
For my post-doc, I decided to change domains and entered the field of hearing loss and tinnitus, which both have limited knowledge on the underlying mechanisms. At the Karolinska Institutet, preclinical work revealed the importance of chronotherapy in the treatment of noise-induced hearing loss. We recently found that cisplatin ototoxicity is greater when delivered during the awake phase, rather than during the sleep phase, revealing that chrono-delivered cisplatin may decrease the ototoxic side-effects of cisplatin.
In 2014, I was awarded a faculty funded Assistant Professorship at Karolinska Institutet, during which I aimed to investigate the molecular mechanisms causing auditory neuropathy and tinnitus. In order to understand the mechanisms of tinnitus generation and persistence, I recently evidenced in twins and adoptees that the familial transmission of tinnitus is influenced by genetics. With this aim in mind, I created the project STOP (Sweden Tinnitus Outreach Project, http://stop.ki.se) aiming at studying epidemiology, auditory profiles, diagnostic and genetics.