Tinnitus

Tinnitus and Zenzi CBD Gummies


Tinnitus and Zenzi CBD Gummies

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Name of treatment

Zenzi CBD Gummies

Does the BTA recommend this treatment?

No

BTA opinion on this treatment:

Very little research has been done, but the evidence so far suggests that cannabinoids may exacerbate tinnitus.

Licences for the use of CBD oil or hemp oil as a medicine have not yet been granted.

Type of treatment

Pharmaceutical

Claims for treatment

“Decrease stress and help with other health difficulties”[1]

How treatment is delivered

Small gummie sweets. Gummies contain 100% organic hemp oil [2] and 300mg of organic hemp extract[3]

Potential negative consequences

Animal models suggest that cannabinoids may promote the development of tinnitus[4] [5].

Users of marijuana are more likely to experience tinnitus[6]

Evidence offered:

 

Papers available

10 relevant papers found with keywords tinnitus + cannabinoid in PubMed database

Conclusions drawn

To date, there have been no systematic studies of the effects of cannabinoids on tinnitus in humans.[7] It is feasible that different cannabinoids may have different effects on tinnitus.[8]

Quality of evidence[9]

C/D

Would the BTA support further studies into this treatment?

Yes, if high quality study.

Verdict: Safety – is this treatment harmful?

  Evidence of harm

Verdict: Efficacy – does this treatment work?

  Evidence that it has no effect

Comments

Products containing CBD oil are legal in the UK, providing the content of a psychoactive component of cannabis (THC, tetrahydrocannabinol) is 0.2% or below.

 

We welcome feedback on all our information. Please send any corrections or updates for consideration to Nic Wray, Communications Manager on [email protected]

 

[1] Zenzi CBD Gummies. Zenzi CBD Gummies – Shark Tank, Benefits, Review and Where To Buy.

https://sites.google.com/view/zenzi-cbd-gummies-info/

[2] ibid

[3] ibid

[4]  Zheng Y, Reid P, Smith PF. Cannabinoid CB1 receptor agonists do not decrease, but may increase acoustic trauma-induced tinnitus in rats. Frontiers in Neurology 2015. https://doi.org/10.3389/fneur.2015.00060

[5] Narwani V, Bourdillon A, Nalamada K, Manes RP, Hildrew DM. Does cannabis alleviate tinnitus? A review of the current literature. Laryngoscope Investigative Otolaryngology. 2020 Oct 30;5(6):1147-1155. doi: 10.1002/lio2.479. 

[6] Qian ZJ, Alyono JC. An Association between marijuana use and tinnitus. American Journal of Otolaryngology. 2020; 41(1): 102314. doi:10.1016/j.amjoto.2019.102314

[7] Smith PF, Zheng Y. Cannabinoids, cannabinoid receptors and tinnitus. Hearing Research, 2016; 332 210-216.

[8] Narwani V, Bourdillon A, Nalamada K, Manes RP, Hildrew DM. Does cannabis alleviate tinnitus? A review of the current literature. Laryngoscope Investigative Otolaryngology. 2020 Oct 30;5(6):1147-1155. doi: 10.1002/lio2.479. 

[9] A = Systematic review/meta analysis. B = Randomised control studies. C = Cohort studies. D = Case control studies. E = case studies/reports. +/- to be used to indicate quality within bands

Download this information:

TINNITUS AND ZENZI CBD GUMMIES

Image by Alexas_Fotos on Pixabay.

Image is of gummie sweets and is not intended to be an accurate representation of the product.

Updated 8 October 2021





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