Tinnitus and Vitamin B12

Name of treatment

Vitamin B12 (cobolamin, methylcobalamin, cyanocobalamin)

Type of treatment

Dietary supplement

Claims for treatment

Reduces/eliminates the tinnitus percept

Shortage of this nutrient has been linked with chronic tinnitus and noise induced hearing loss  [1] [2] [3]

How treatment is delivered

Orally; Intramuscular therapy[3]

Potential negative consequences

Generally regarded as safe


Evidence offered:


Papers available

<30 (1964-2022)

Conclusions drawn

Vitamin B12 deficiency is more common in people with tinnitus than the general population [1] [2] [3]

A higher intake of vitamin B12 is associated with reduced odds of tinnitus. [4]

Although tinnitus severity improves in some people following Vitamin B12 therapy, the results are not significant.[3]

Quality of evidence[5]


Does the BTA recommend this treatment?


BTA opinion on this treatment:

Although independent evidence is limited and of poor quality, what there is does not show that Vitamin B12 is effective for tinnitus. We would suggest you talk to your GP before taking any new medication or supplement.

Would the BTA support further studies into this treatment?


Verdict: Safety – is this treatment harmful?

 Regarded as safe

Verdict: Efficacy – does this treatment work?

 No evidence of effect


For further information

The BTA Tinnitus Support Team can answer your questions on any tinnitus related topics:

Telephone: 0800 018 0527
Web chat: – click on the icon
Email: [email protected]
Text/SMS: 07537 416841

We also offer a free tinnitus e-learning programme, Take on Tinnitus.

Download this information

This information is in PDF format.


We welcome feedback on all our information. You can pass your comments to our Communications Team:

Telephone: 0114 250 9933
Email: [email protected]
or by writing to us at the address below.


[1] Shemesh Z, Attias J, Ornan M, Shapira N, Shahar A. Vitamin B12 deficiency in patients with chronic tinnitus and noise-induced hearing loss. American Journal of Otolaryngology, 1993: 14(2)m 94-9

[2] Berkiten G, Yildirim G, Topaloglu I, Ugras H. Vitamin B12 levels in patients with tinnitus and effectiveness of vitamin B12 treatment on hearing threshold and tinnitus. B-ENT, 2013: 9(2), 111-6

[3] Singh C, Kawatra R, Gupta J, Awasthi V, Dungana H. Therapeutic role of Vitamin B12 in patients of chronic tinnitus: A pilot study. Noise Health, 2016: 18(81), 93-7

[4] Dawes P, Cruickshanks KJ, Marsden A, Moore DR, Munro KJ. Relationship Between Diet, Tinnitus, and Hearing Difficulties. Ear and Hearing. 2020 Mar/Apr;41(2):289-299. doi: 10.1097/AUD.0000000000000765. PMID: 31356390; PMCID: PMC7664714.

[5] A = Systematic review/meta analysis. B = Randomised control studies. C = Cohort studies. D = Case control studies. E = case studies/reports. +/- to be used to indicate quality within bands

Author: Nic Wray

Version 2.0

Updated: 11 July 2022

To be reviewed: July 2025

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